Low Dose Naltrexone (LDN) is gaining attention for its potential therapeutic benefits for a variety of chronic conditions. Unlike standard doses of naltrexone, LDN is prescribed at much lower doses, which appear to have unique effects on the immune system and inflammation.Â
At Avrio Pharmacy in Scottsdale, we compound LDN for licensed practitioners across Arizona (and our other licensed states). We are proud members of the LDN Research Trust, supporting ongoing research and development to improve patient outcomes through innovative LDN therapies.Â
What Is Low Dose Naltrexone and How Does It Work?Â
At low doses, naltrexone temporarily blocks opioid receptors in the body. This causes the body to increase production of endorphins, natural chemicals that help reduce pain and promote a sense of well-being.Â
The increased endorphin levels may help regulate the immune system and reduce inflammation. LDN also antagonizes immune toll-like receptor-4 (TLR-4), which can further reduce inflammatory cytokines and decrease the body’s immune response. These mechanisms contribute to LDN’s potential benefits across a variety of conditions.Â
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Custom Solutions for Low Dose NaltrexoneÂ
Many naturopathic and functional medicine providers rely on LDN for a variety of therapeutic approaches. Each patient’s protocol may require a unique dosage, delivery form, or combination with other compounds.Â
Avrio Pharmacy prepares custom LDN formulations that can be tailored to:Â
- Exact dosage specifications required by the practitionerÂ
- Sublingual tablets, capsules, or liquids based on patient preferenceÂ
- Combination therapies as prescribedÂ
By compounding LDN, practitioners can provide personalized care while ensuring accuracy and consistency in every dose.Â
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Four Scored Low Dose Naltrexone TabletsÂ
At Avrio Pharmacy, we offer four-scored LDN tablets designed for precise and flexible dosing.Â
Benefits of Four-Scored TabletsÂ
Four-scored design allows for easy dose titration.Â
Enables 1/4 tablet increments for gradual dose adjustment.Â
Small tablet size can improve patient compliance.Â
Compounded Tablet StrengthsÂ
2 mg four-scored (0.5 mg segments)Â
4.5 mg four-scored (most common target dose)Â
6 mg four-scored (1.5 mg segments)Â
These tablets allow patients to gradually reach their target dose, ensuring a personalized approach to treatment.Â
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The Avrio Pharmacy DifferenceÂ
As a trusted compounding pharmacy in Scottsdale, we focus on precision, accuracy, and supporting practitioner needs. Licensed providers across Arizona rely on Avrio Pharmacy for custom LDN formulations prepared for their specifications.Â
We also consult with practitioners on dosage forms, formulation possibilities, and compounding strategies, supporting safe and effective patient care.Â
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DisclaimerÂ
Avrio Pharmacy is a compounding pharmacy that prepares customized medications per a licensed practitioner’s prescription. Compounded medications are not FDA-approved.Â
Last updated November 2025.Â