What Is Methylene Blue?

Methylene Blue (MB) is a versatile drug used in a range of medical and therapeutic applications. MB has been under investigation for a wide range of applications for 120+ years. At Avrio Pharmacy, we compound methylene blue to meet your specific needs. Our most common formulation is MB compounded capsules.

Potential Uses and Benefits for Patients

  • Anti-aging – may have protective properties against accelerated aging.
  • COVID and Long-COVID Infections: It may inhibit the SARS-COV-2 virus by several mechanisms. May have preventative uses, applicable uses while infected, and to improve post-infection symptoms.
  • Methemoglobinemia: Methylene blue is commonly used to treat methemoglobinemia, a condition where abnormal levels of methemoglobin in the blood reduce its ability to carry oxygen. MB is shown to protect against hypoxic or ischemic tissue damage.
  • Alzheimer’s Disease – may have potential benefits on improving cellular function and cognitive benefits.
  • Mitochondrial Enhancer – may promote increased functionality of your body’s energy powerhouse.
  • Mood and Depression – has been shown to improve overall sense of wellbeing. MB may interact with other medications used to help similar conditions, so always consult with your provider and pharmacy prior to combining MB with an existing medication.
  • Oxidative Stress and Cellular Metabolism: Methylene blue acts as an antioxidant and has potential benefits in reducing oxidative stress and supporting cellular metabolism.
  • Diagnostic Tool: It is also used as a diagnostic tool in various medical procedures and tests. One of it’s earliest applications.
  • Other Conditions: Depending on the formulation and use, methylene blue may be used for additional conditions as determined by a healthcare provider.

 

Methylene blue’s applications can vary based on its form and the specific needs of the patient. Always follow the instructions provided by your healthcare provider to ensure safe and effective use.

Taking Methylene Blue & Dosage Information

Methylene blue can be administered in several ways depending on the prescribed form and purpose of treatment. The most common form of medication is an oral capsule.

If prescribed orally, methylene blue should be taken as directed. Often, providers will suggest a “holiday” where you skip the dosing one day per week. Follow the guidance of your provider.

Dosage Information

Dosage for methylene blue varies depending on the condition being treated and individual patient factors. Here are some general guidelines:

Standard Dose: The dosage of methylene blue is usually tailored to individual needs. Your healthcare provider will determine the appropriate dose based on your condition.

Administration Frequency: Methylene blue may be administered once or multiple times a day, depending on the treatment plan.

Adjustments: Dosage adjustments may be made based on your response to treatment, side effects, and based on other concomitant therapies.

Consult with your healthcare provider for personalized dosage recommendations and any adjustments needed.

Explore Methylene Blue FAQs!

Methylene blue is used for a variety of medical purposes, including treating methemoglobinemia, improve mitochondrial function, improve cognition, improve mood, certain infections (like COVID), and as a diagnostic tool among many others. Its applications can vary depending on the condition being treated. 

Follow the specific instructions provided by your healthcare provider. Methylene blue is most commonly administered by oral route with a capsule.  

Possible side effects can include nausea, headaches, blue/green urine, dizziness, and discoloration in the mouth or skin (site of application), increased perspiration, and extremity pain. Severe side effects like allergic reaction, sudden fever, yellowing/pale skin, weakness or confusion, chest pain, or shortness of breath are rare but should be reported to your healthcare provider immediately. 

Always ensure your provider and pharmacy are aware of all medications, supplements/vitamins, and over the counter medication that you may take, as there are certain medications that may interact. If you have a known G6PD deficiency consult with your provider as you may be at an increased risk of severe adverse events. Do not take if you are pregnant or breastfeeding without consulting with your provider. 

Store methylene blue as directed by your healthcare provider or according to the instructions provided with the medication. It is typically kept in a cool, dry place away from light often times under refrigeration.

If you miss a dose, take it as soon as you remember unless it’s almost time for your next dose. Do not double up to make up for a missed dose. Consult your healthcare provider for specific instructions. 

The time required to see results can vary based on the condition being treated and individual response. Your healthcare provider can give you a better estimate based on your treatment plan. 

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