Understanding Feline Infectious Peritonitis (FIP) 

What is FIP? 

Feline Infectious Peritonitis (FIP) is a complex and fatal disease caused by certain strains of the feline coronavirus (FCoV). Not all strains of FCoV lead to FIP; in fact, most cats that are exposed to the virus do not develop the disease. FIP occurs when the virus mutates and triggers a severe inflammatory response in the cat’s body, primarily affecting the area surrounding the abdominal organs. 

Causes and Transmission 

FIP is caused by a mutation of the feline coronavirus, which is relatively common in cats. The virus spreads through feces, saliva, and other bodily fluids. Cats in close quarters, such as those in shelters or multi-cat households, are at a higher risk of exposure. It’s important to note that while the coronavirus can be contagious, FIP itself is not spread from one cat to another. For information on prevention view our blog. 

Symptoms of FIP 

FIP presents in two primary forms, each with distinct symptoms: 

Wet Form (Effusive FIP) 

This form is characterized by the accumulation of fluid in the abdomen (ascites) or chest (pleural effusion). Symptoms may include: 

• Abdominal distension or bloating 

• Difficulty breathing 

• Lethargy 

• Decreased appetite 

Dry Form (Non-effusive FIP) 

The dry form involves the formation of granulomas—clusters of immune cells—that can affect various organs. Symptoms may include: 

• Fever that doesn’t respond to treatment 

• Weight loss 

• Eye problems (e.g., inflammation or vision loss) 

• Neurological signs such as difficulty walking or seizures 

Diagnosis 

Diagnosing FIP can be challenging due to its symptoms overlapping with other conditions. Veterinarians rely on a combination of clinical signs, laboratory tests, and imaging techniques. Common diagnostic approaches include: 

• Blood Tests: Elevated levels of certain proteins can indicate FIP. 

• Abdominal Ultrasound: To detect fluid accumulation and assess the health of internal organs. 

• Fluid Analysis: If fluid is present in the abdomen or chest, its characteristics can provide clues to the diagnosis. 

Treatment and Management 

Recent developments in FIP treatment have introduced GS-441524, an antiviral medication that directly targets the feline coronavirus. This drug has shown effectiveness in managing the disease and improving outcomes for affected cats. 

Early diagnosis and treatment are crucial for the best chance of managing FIP effectively. Consult with your veterinarian to explore the most appropriate treatment options for your cat. 

Avrio Pharmacy GS-441524 

Avrio Pharmacy is proud to be compounding GS-441524 tablets, providing a crucial treatment option for cats with FIP. Our commitment to providing high-quality, customized medication ensures that cats with FIP can receive a treatment option tailored to their needs.  

Our tablets are $9 each for 50mg, and are four-scored. Click here for our free dosage calculator.